Fusidic acid is an antibiotic that belongs to a group of its own, the fusidanes. The molecule has a steroid-like structure but does not possess any steroid activity. The structure is thought to be responsible for the steroid-like high penetration, and for the fact that no cross-resistance or crossal
Fusidic acid induced jaundice
β Scribed by M. Haddad; S. Shabat; A. Koren; E. Stelman; A. Zelikovski
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 191 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0934-9723
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The structural elucidation of a closely related group of steroidal antibiotics, fusidic acid2 (I), cephalosporin P.,3 and helvolic acid4 has established that these antibiotics possess unique structures and stereochemistry. Recent attention has focused on the synthesis of the novel tetracyclic m, syn
## Abstract Two analogues of the antibiotic fusidic acid with photolabile groups, 4βazidophenyl and 4βbenzoylphenyl, were successfully labelled with tritium via Pd/C catalysed tritiation of unsaturated precursors. Specific activities of 36 and 44 Ci/mmol were obtained. Copyright Β© 2007 John Wiley &