Fusidic-acid-resistant staphylococci
β Scribed by G. R. Miller
- Publisher
- Springer Netherlands
- Year
- 1971
- Tongue
- English
- Weight
- 203 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0003-6072
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Fusidic acid is an antibiotic that belongs to a group of its own, the fusidanes. The molecule has a steroid-like structure but does not possess any steroid activity. The structure is thought to be responsible for the steroid-like high penetration, and for the fact that no cross-resistance or crossal
The structural elucidation of a closely related group of steroidal antibiotics, fusidic acid2 (I), cephalosporin P.,3 and helvolic acid4 has established that these antibiotics possess unique structures and stereochemistry. Recent attention has focused on the synthesis of the novel tetracyclic m, syn