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Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia

✍ Scribed by Bowen, T; Guy, C A; Craddock, N; Cardno, A G; Williams, N M; Spurlock, G; Murphy, K C; Jones, L A; Gray, M; Sanders, R D


Book ID
110058914
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
47 KB
Volume
3
Category
Article
ISSN
1359-4184

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πŸ“œ SIMILAR VOLUMES


No association between a polymorphic CAG
✍ Guy, C.A.; Bowen, T.; Williams, N.; Jones, I.R.; McCandless, F.; McGuffin, P.; O πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 11 KB πŸ‘ 2 views

A recent case-control study suggested that modest enlargements of a CAG repeat in the hKCa3 potassium channel may be associated with bipolar disorder. We tried to replicate this result in a UK Caucasian sample of 203 DSM-IV bipolar I disorder patients and 206 controls group-matched for age and sex.

Support for an association between HLA-D
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An increase of HLA-DR1 has been observed in schizophrenia patients from the Japanese population. A decrease of DR4, which was reported in Caucasian patients, has also been found in some of the Japanese studies. This small study further investigated frequencies of HLA-DR1 and DR4 in unrelated Japanes