✦ LIBER ✦

Further studies on palytoxin. II. structure of palytoxin

✍ Scribed by Daisuke Uemura; Katsuhiro Ueda; Yoshimasa Hirata; Hideo Naoki; Takashi Iwashita

Publisher: Elsevier Science
Year: 1981
Tongue: French
Weight: 247 KB
Volume: 22
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)90551-9

No coin nor oath required. For personal study only.

✦ Synopsis

The structural elucidation of palytoxin has involved some complicated and difficult problems because it is a non-crystalline, water soluble, unstable and novel molecule.

2 However, we could ultimately elucidate its total structure by

📜 SIMILAR VOLUMES

Further studies on palytoxin. I.

✍ Daisuke Uemura; Katsuhiro Ueda; Yoshimasa Hirata; Hideo Naoki; Takashi Iwashita 📂 Article 📅 1981 🏛 Elsevier Science 🌐 French ⚖ 221 KB

Structural studies on palytoxin, a poten

Structural studies on palytoxin, a potent coelenterate toxin

✍ Daisuke Uemura; Katsuhiro Ueda; Yoshimasa Hirata; Chuji Katayama; Jiro Tanaka 📂 Article 📅 1980 🏛 Elsevier Science 🌐 French ⚖ 240 KB

Effects of palytoxin on porcine coronary

Effects of palytoxin on porcine coronary artery rings

✍ Casey P. Robinson; David R. Franz; Maria E. Bondura 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 477 KB

Palytoxin, in concentrations as low as 100 fM, caused contractions of porcine coronary artery rings. Palytoxin concentrations of < 1 nM caused slowly developing contractions which were not maximal even after 2 h. Rings contracted by 100 nM palytoxin achieved maximal tension by 10 min and relaxed to

Synthetic studies on palytoxin. Stereoco

Synthetic studies on palytoxin. Stereocontrolled, practical synthesis of the C.101–C.115 segment

✍ Soo Sung Ko; Larry L Klein; Klaus-Peter Pfaff; Yoshito Kishi 📂 Article 📅 1982 🏛 Elsevier Science 🌐 French ⚖ 225 KB

A stereocontrolled and practical synthetic route to the acetal 2a, a degradation product of palytoxin, in optically active form is described. Palytoxin, the toxic principle isolated from marine soft corals of the genus Palythoa, is the most poisonous substance known to date, except for a few polype

Synthetic studies on palytoxin stereocon

Synthetic studies on palytoxin stereocontrolled practical synthesis of the C.23 – C.37 segment

✍ J. Leder; H. Fujioka; Y. Kishi 📂 Article 📅 1983 🏛 Elsevier Science 🌐 French ⚖ 247 KB

An 8-step synthesis of the bicyclic ketal 2 from l-(+)-citronella1 is described. -

Synthetic studies on palytoxin stereocon

Synthetic studies on palytoxin stereocontrolled practical synthesis of the C.85 – C.98 segment

✍ W.W. McWhorter Jr.; S.H. Kang; Y. Kishi 📂 Article 📅 1983 🏛 Elsevier Science 🌐 French ⚖ 184 KB

A stereocontrolled 12-step synthesis of the C.85-C.98 segment of palytoxin is described, Recent work in this laboratory has established the complete structure and laid a solid foundation for the chemical synthesis of the structurally novel and highly physioloqically active marine natural product pal