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Further information on the steric course of the baker's yeast reduction of 4-substituted-3-oxobutanoates

✍ Scribed by Claudio Fuganti; Piero Grasselli; P.Fausto Seneci; Paolo Casati


Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
126 KB
Volume
27
Category
Article
ISSN
0040-4039

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The nsults from the baker's yeast-mediated reduction of the acetates 3a-d and the methyl ethers 5a-d wete compared with the same biotransformation which converts the a-hydroxy ketones lad into the (R)-diols 2ad (90-989bee); the acetates 3ad afford the (S)-monoacetates 4o-d (7294% ee) and the methyl