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Functionalized Chiral Ionic Liquids as Highly Efficient Asymmetric Organocatalysts for Michael Addition to Nitroolefins

✍ Scribed by Sanzhong Luo; Xueling Mi; Long Zhang; Song Liu; Hui Xu; Jin-Pei Cheng


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
124 KB
Volume
118
Category
Article
ISSN
0044-8249

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## Abstract A highly diastereoselective and enantioselective Michael addition of cyclohexanone, acetone and other ketones to nitroolefins was developed by the use of an amine organocatalyst based on bispidine. Additionally, a theoretical study of transition structures revealed that this bispidine‐b