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Functional Interdependence and Colocalization of Endothelial Nitric Oxide Synthase and Heat Shock Protein 90 in Cerebral Arteries

✍ Scribed by Khurana, Vini G.; Feterik, Kristian; Springett, Margaret J.; Eguchi, Daihiko; Shah, Vijay; Katusic, Zvonimir S.


Book ID
110079107
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
812 KB
Volume
20
Category
Article
ISSN
0271-678X

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## Abstract Hyperglycemia is the hallmark of diabetes mellitus. Poor glycemic control is correlated with increased cardiovascular morbidity and mortality. High glucose can trigger endothelial cell apoptosis by de‐activation of endothelial nitric oxide synthase (eNOS). eNOS was recently demonstrated