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Functional consequences of cyclin D1 overexpression in human mammary luminal epithelial cells

✍ Scribed by Tahereh Kamalati; Derek Davies; Jenny Titley; Mark R. Crompton

Book ID: 110236513
Publisher: Springer
Year: 1997
Tongue: English
Weight: 134 KB
Volume: 16
Category: Article
ISSN: 0262-0898
DOI: 10.1023/a:1006529407652

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## Background: Overexpression of cyclin d1 has been documented in a number of human cancers. increased expression of cyclin d1 can contribute to cellular transformation and abnormal proliferation. ## Methods: Quantitative rt-pcr and/or western blot analysis were used to determine the level of cyc