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Functional characterization of two novel splicing mutations of glucokinase gene associated with maturity-onset diabetes of the young type 2 (MODY2)

✍ Scribed by Igudin, E. L.; Spirin, P. V.; Prasolov, V. S.; Zubkova, N. A.; Petryaikina, E. E.; Tyul’pakov, A. N.; Rubtsov, P. M.


Book ID
125393332
Publisher
SP MAIK Nauka/Interperiodica
Year
2014
Tongue
English
Weight
305 KB
Volume
48
Category
Article
ISSN
0026-8933

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## Maturity -onset diabetes of the young (MODY) resulting from mutations in the glucokinase (GCK) gene accounts for approximately 20% of MODY in the UK. W e have performed fluorescent single stranded conformation polymorphism (F-SSCP) analysis or direct sequencing of the GCK gene in 212 patients re