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Functional characterization of the human spermidine/spermine N1-acetyltransferase gene promoter

✍ Scribed by Hideyuki Tomitori; Mitsuru Nenoi; Kazuei Mita; Kazuhiro Daino; Kazuei Igarashi; Sachiko Ichimura

Book ID
114147664
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
300 KB
Volume
1579
Category
Article
ISSN
0167-4781

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Regulation of spermidine/spermine N1-acetyltransferase expression by cytokines and polyamines in human hepatocarcinoma cells (HepG2)
✍ M. Alfonsina Desiderio; Giovanna Pogliaghi; Paola Dansi πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 291 KB πŸ‘ 2 views

Spermidine/spermine N 1 -acetyltransferase (cSAT), a key enzyme in polyamine degradation, is induced by various hepatotoxins and liver tumor promoters. In this paper we demonstrate that physiological factors, such as cytokines, control cSAT expression in HepG2 human hepatocarcinoma cells. Hepatocyte