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Regulation of spermidine/spermine N1-acetyltransferase by intracellular polyamine pools: Evidence for a functional role in polyamine homeostasis

โœ Scribed by N.W. Shappell; M.F. Fogel-Petrovic; C.W. Porter


Book ID
115927296
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
659 KB
Volume
321
Category
Article
ISSN
0014-5793

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Regulation of spermidine/spermine N1-ace
โœ M. Alfonsina Desiderio; Giovanna Pogliaghi; Paola Dansi ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 291 KB ๐Ÿ‘ 2 views

Spermidine/spermine N 1 -acetyltransferase (cSAT), a key enzyme in polyamine degradation, is induced by various hepatotoxins and liver tumor promoters. In this paper we demonstrate that physiological factors, such as cytokines, control cSAT expression in HepG2 human hepatocarcinoma cells. Hepatocyte