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Fucoidan induces nitric oxide production via p38 mitogen-activated protein kinase and NF-κB-dependent signaling pathways through macrophage scavenger receptors

✍ Scribed by Toshinobu Nakamura; Hiroshi Suzuki; Youichiro Wada; Tatsuhiko Kodama; Takefumi Doi


Book ID
116292509
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
232 KB
Volume
343
Category
Article
ISSN
0006-291X

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## Abstract Cytokine‐induced expression of inducible nitric oxide synthase (iNOS) and concomitant production of nitric oxide (NO) involve activation of mitogen‐activated protein (MAP) kinases and are in most cases mediated by the transcription factor NF‐κB. We investigated the role of p38 MAP kinas