The role of tau (MAPT) in frontotemporal
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R. Rademakers; M. Cruts; C. van Broeckhoven
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Article
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2004
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John Wiley and Sons
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English
β 343 KB
Tau is a multifunctional protein that was originally identified as a microtubule-associated protein. In patients diagnosed with frontotemporal dementia and parkinsonism linked to chromosome 17, mutations in the gene encoding tau (MAPT) have been identified that disrupt the normal binding of tau to t