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The status of “Pick’s Disease” and other tauopathies within the frontotemporal dementias

✍ Scribed by David M.A Manna; Stuart Pickering-Brown

Book ID
117411127
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
43 KB
Volume
22
Category
Article
ISSN
0197-4580

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Tau is a multifunctional protein that was originally identified as a microtubule-associated protein. In patients diagnosed with frontotemporal dementia and parkinsonism linked to chromosome 17, mutations in the gene encoding tau (MAPT) have been identified that disrupt the normal binding of tau to t