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Frontotemporal dementia, motor neuron disease and tauopathy: clinical and neuropathological study in a family

✍ Scribed by O. Martinaud; A. Laquerrière; L. Guyant-Maréchal; P. Ahtoy; P. Vera; N. Sergeant; A. Camuzat; P. Bourgeois; J. J. Hauw; D. Campion; D. Hannequin

Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
655 KB
Volume
110
Category
Article
ISSN
0001-6322

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It has been recently demonstrated that the 43-kDa transactive response (TAR)-DNA-binding protein (TARDBP) is the neuropathological hallmark of Frontotemporal Dementia (FTD) with ubiquitin-positive and tau-negative inclusions. Large series of FTD patients without motor neuron disease have been previo