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Familial frontotemporal dementia with ubiquitin inclusion bodies and without motor neuron disease

✍ Scribed by E. Kövari; G. Leuba; A. Savioz; K. Saini; R. Anastasiu; J. Miklossy; C. Bouras


Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
147 KB
Volume
100
Category
Article
ISSN
0001-6322

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It has been recently demonstrated that the 43-kDa transactive response (TAR)-DNA-binding protein (TARDBP) is the neuropathological hallmark of Frontotemporal Dementia (FTD) with ubiquitin-positive and tau-negative inclusions. Large series of FTD patients without motor neuron disease have been previo