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From quantitative protein complex analysis to disease mechanism

โœ Scribed by Texier, Y.; Kinkl, N.; Boldt, K.; Ueffing, M.

Book ID
123098945
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
257 KB
Volume
75
Category
Article
ISSN
0042-6989

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## Abstract Protein scaffold complexes are a key mechanism by which a common signaling pathway can serve many different functions. Sequestering a signaling enzyme to a specific subcellular environment not only ensures that the enzyme is near its relevant targets, but also segregates this activity t