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From Hayflick to Walford: the role of T cell replicative senescence in human aging

✍ Scribed by Rita B Effros


Book ID
113614462
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
106 KB
Volume
39
Category
Article
ISSN
0531-5565

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Replicative senescence of T cells: does
✍ Rita B. Effros; Graham Pawelec πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 702 KB

Extensive in vitro research on fibroblasts has defined numerous genetic and phenotypic changes associated with replicative senescence. Identification of T-cell replicative senescence as a feature of human immunodeficiency virus (HIV) disease and ageing suggests this phenomenon merits more careful co