𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Frequent nuclear accumulation of β-catenin in pituitary adenoma

✍ Scribed by Shuho Semba; Shuang-Yin Han; Hidetoshi Ikeda; Akira Horii

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
269 KB
Volume
91
Category
Article
ISSN
0008-543X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

β-catenin accumulation and mutation of t
β-catenin accumulation and mutation of the CTNNB1 gene in hepatoblastoma
✍ Hendrik Bläker; Walter J. Hofmann; Ralf J. Rieker; Roland Penzel; Matthias Graf; 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 275 KB 👁 1 views

Hepatoblastoma is a rare malignant tumor of the liver that occurs in children at an average age of 2 to 3 years. Epidemiologic studies have shown an increased frequency of this tumor type in families affected by adenomatous polyposis coli. In addition to the epidemiologic data, molecular genetic stu

Nuclear localization of β-catenin is an
Nuclear localization of β-catenin is an important prognostic factor in hepatoblastoma
✍ Won Sang Park; Ro Ra Oh; Jik Young Park; Pum Joon Kim; Min Sun Shin; Jong Heun L 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 272 KB 👁 1 views

In this study, mutational and immunohistochemical analyses of b-catenin were performed in 30 hepatoblastomas, to assess the prevalence of alterations of the Wnt pathway with respect to clinicopathological parameters and survival. Four missense mutations of b-catenin (13.3%) were detected and there w

Patterns of α- and β-catenin and E-cadhe
Patterns of α- and β-catenin and E-cadherin expression in colorectal adenomas and carcinomas
✍ Van Der Wurff, Anna A. M.; Vermeulen, Stefan J. T.; Van Der Linden, Edith P. M.; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 245 KB

Previous in vitro and in vivo model studies have shown that when E-cadherin expression in carcinoma cells is reduced, invasive behaviour ensues. The situation in human cancer in vivo, however, appears to be more complex, as immunohistochemically determined E-cadherin expression in various carcinomas

Frequent mutations of the rat β-catenin
Frequent mutations of the rat β-catenin gene in colon cancers induced by methylazoxymethanol acetate plus 1-hydroxyanthraquinone
✍ Masumi Suzui; Toshikazu Ushijima; Roderick H. Dashwood; Naoki Yoshimi; Takashi S 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 172 KB

Recent evidence suggests that the β-catenin gene (CTNNB1) acts as an oncogene, and some human colon tumors with an intact APC gene have activating mutations in CTNNB1. In this study, mutations in the region corresponding to N-terminal phosphorylation sites (codons 1-51) of the rat Ctnnb1 gene were i

β-Catenin mutation and expression analys
β-Catenin mutation and expression analysis in ovarian cancer: Exon 3 mutations and nuclear translocation in 16% of endometrioid tumours
✍ Kim Wright; Peter Wilson; Sarah Morland; Ian Campbell; Michael Walsh; Terry Hurs 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 134 KB

The molecular mechanisms involved in the generation of epithelial ovarian cancers are poorly understood, but evidence suggests that the different histological subtypes may arise from independent tumorigenic events. ␤-Catenin is emerging as an important oncogene in the transformation of a number of e