Frequent loss of heterozygosity in chromosomal region 9pter-p13 in tumor biopsies and cytological material of uterine cervical cancer
β Scribed by Maria M. Manolaraki; Demetrios A. Arvanitis; George Sourvinos; Stavros Sifakis; Eugenios Koumantakis; Demetrios A. Spandidos
- Book ID
- 117467151
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 178 KB
- Volume
- 176
- Category
- Article
- ISSN
- 0304-3835
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## Abstract Loss of heterozygosity (LOH) at chromosome 3p21 is frequent in cervical cancers. The candidate tumor suppressor gene, __RASSF1A__ located at 3p21.3, is found to be inactivated in several major human cancers, implicating its significance in carcinogenesis. We aimed to investigate the sta