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Frequent epigenetic inactivation of chromosome 3p candidate tumor suppressor genes in gallbladder carcinoma

✍ Scribed by Erick Riquelme; Moying Tang; Sergio Baez; Alfonso Diaz; Martha Pruyas; Ignacio I. Wistuba; Alejandro Corvalan

Book ID
116334299
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
396 KB
Volume
250
Category
Article
ISSN
0304-3835

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## Abstract Loss of heterozygosity (LOH) on chromosome 3p is a common event in cervical cancer and typically occurs in a dispersed pattern involving several loci. This implies that more than one resident tumor‐suppressor gene is involved in the genesis of these tumors; however, specific targets rem