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Frequent CpG Island Methylation in Serrated Adenomas of the Colorectum

✍ Scribed by Seun-Ja Park; Asif Rashid; Jae-Hyuk Lee; Sang Geol Kim; Stanley R. Hamilton; Tsung-Teh Wu

Book ID
117021916
Publisher
American Society for Investigative Pathology
Year
2003
Tongue
English
Weight
626 KB
Volume
162
Category
Article
ISSN
0002-9440

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Frequentp53 gene mutations in serrated a
Frequentp53 gene mutations in serrated adenomas of the colorectum
✍ Hiyama, Toru; Yokozaki, Hiroshi; Shimamoto, Fumio; Haruma, Ken; Yasui, Wataru; K πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 670 KB

Serrated adenoma has been recently proposed as a distinct histological lesion of the colorectum. This study examined p53 immunoreactivity, mutations of exons 5-8 of the p53 gene, codon 12 of the Ki-ras gene by PCR-SSCP analyses, and microsatellite instability in 19 serrated adenomas, ten adenocarcin