Frequentp53 gene mutations in serrated a
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Hiyama, Toru; Yokozaki, Hiroshi; Shimamoto, Fumio; Haruma, Ken; Yasui, Wataru; K
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Article
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1998
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John Wiley and Sons
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English
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Serrated adenoma has been recently proposed as a distinct histological lesion of the colorectum. This study examined p53 immunoreactivity, mutations of exons 5-8 of the p53 gene, codon 12 of the Ki-ras gene by PCR-SSCP analyses, and microsatellite instability in 19 serrated adenomas, ten adenocarcin