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CpG Island Methylation in Aberrant Crypt Foci of the Colorectum

โœ Scribed by Annie On-On Chan; Russell R. Broaddus; Patrick S. Houlihan; Jean-Pierre J. Issa; Stanley R. Hamilton; Asif Rashid

Book ID
117021104
Publisher
American Society for Investigative Pathology
Year
2002
Tongue
English
Weight
625 KB
Volume
160
Category
Article
ISSN
0002-9440

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## Abstract Aberrant methylation of CpG islands is a common alteration in human colon cancer. Methylation of only a limited number of loci has been studied in aberrant crypt foci (ACF), the earliest identified premalignant lesions in the colon, and in only a limited number of lesions from the same