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Frequent and histological type-specific inactivation of 14-3-3σ in human lung cancers

✍ Scribed by Osada, Hirotaka; Tatematsu, Yoshio; Yatabe, Yasushi; Nakagawa, Taku; Konishi, Hiroyuki; Harano, Tomoko; Tezel, Ekmel; Takada, Minoru; Takahashi, Takashi

Book ID
110066508
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
336 KB
Volume
21
Category
Article
ISSN
0950-9232

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## Abstract 14‐3‐3 Proteins play important roles in a wide range of vital regulatory processes, including signal transduction, apoptosis, cell cycle progression and DNA replication. In mammalian cells, 7 14‐3‐3 isoforms (β, γ, ϵ, η, σ, θ and ζ) have been identified and each of these seems to have d