Frequency of Immunohistochemical Loss of Mismatch Repair Protein in Double Primary Cancers of the Colorectum and Stomach in Japan
β Scribed by Tetsuji Hayashi; Masami Arai; Masashi Ueno; Hirokatsu Kinoshita; Yurika Tada; Koichi Koizumi; Yoshio Miki; Toshiharu Yamaguchi; Yo Kato; Joji Utsunomiya; Tetsuichiro Muto; Kenichi Sugihara
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 164 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0012-3706
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Little is known about genomic alterations during development of the radial growth phase (RGP) of cutaneous malignant melanomas (CMMs). In this investigation polymerase chain reaction-based microsatellite assays were applied to analyze 13 RGP-CMMs with 18 microsatellite markers at six chromosomal reg
## Abstract Germline mutations in DNA mismatch repair genes underlie one of the most common hereditary cancer predisposition syndromes known in humans, hereditary nonpolyposis colorectal cancer (HNPCC). Defects of the DNA mismatch repair system are also prevalent in sporadic colorectal cancers. The
## Abstract Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant disorder that predisposes to predominantly colorectal and endometrial cancers due to germline mutations in DNA mismatch repair genes, mainly __MLH1__, __MSH2__ and in families with excess endometrial cancer also