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Frequencies of sister-chromatid exchanges in relation to cell kinetics in lymphocyte cultures

✍ Scribed by E. Giulotto; A. Mottura; R. Giorgi; L. de Carli; F. Nuzzo

Book ID
113191752
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
1016 KB
Volume
70
Category
Article
ISSN
0027-5107

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This study examined the effect of pyrimethamine (PYR) on sister chromatid exchanges (SCEs) in human lymphocytes. PYR is a folic acid antagonist used for the treatment of malaria and toxoplasmosis. PYR was added to peripheral blood lymphocyte cultures at three different doses: 0.05, 0.1, and 0.2 mg/m