Cell-stage dependence of mutagen-induced sister-chromatid exchanges in human lymphocyte cultures
β Scribed by Kumiko Iijima; Kanehisa Morimoto
- Book ID
- 113193012
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 712 KB
- Volume
- 162
- Category
- Article
- ISSN
- 0027-5107
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Peripheral blood lymphocytes from three patients with Down syndrome (DS; trisomy 21; aged 5-6 years) and three age-matched control children were studied for the induction of chromosomal aberrations and sister chromatid exchanges (SCEs). Cells in G0 were exposed to bleomycin (20-100 micrograms/ml) fo