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Free trypsin-catalyzed peptide synthesis in acetonitrile with low water content

✍ Scribed by Václav Čeřovský


Publisher
Springer Netherlands
Year
1990
Tongue
English
Weight
329 KB
Volume
12
Category
Article
ISSN
0141-5492

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V8 proteinase-catalyzed peptide synthesi
✍ Václav Cer̆vský 📂 Article 📅 1991 🏛 Elsevier Science 🌐 French ⚖ 230 KB

Free Staphylococcus auseus V8 proteinase was applied to coupling reactions of Z-Glu-OMe, Z-Glu-OBzl, Z-Ala-Glu-OMe and Z-Ala-Ala-Glu-OMe with various amino acid amides and peptides in acetonitrile containing 5 vol. % of water. No synthesis of Z-Asp-Leu-NH, was achieved under the same conditions. The