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Free radical addition of haloalkanes to polymer bound olefins and its application to the solid-phase synthesis of pyrethroids

✍ Scribed by H.M.S Kumar; P.Pawan Chakravarthy; M Shesha Rao; P.Sunder Ram Reddy; J.S Yadav

Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
306 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis

Polymer bound olefins undergo free radical initiated 1,2-addition when reacted with a variety of haloalkanes. The strategy could be applied successfully to the solid-phase synthesis of dihaloethenylcyclopropane carboxylic acids which are the key fragments of synthetic pyrethroids.

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