Radicals / Addition 1 Stereoselectivity f Alkynes Alkanes can be added to alkynes in a thermally initiated freeradical chain reaction ("ane reaction"). The addition of cyclohexane to 1-alkynes la-1 yields a mixture of (4and (E)-2cyclohexyl-1-alkenes 3a-1. An essential step in this reaction is the ad
Free Radical Addition of Cyclopentane and Cyclohexane to Halogeno Derivatives of 1,1-Difluoroethene.
β Scribed by Julian A. Cooper; Elodie Copin; Graham Sandford
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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Free radicals derived from some alkyl substituted cyclohexanol derivatives react with hexafluoropropene to give a variety of polyfluoroalkylated adducts. Stereochemistry of the processes is discussed and remote functionalisation of the methyl group in Chemie freier Radikale. 13. Addition von Alkylcy
Radical additions 1 Acrylonitriles 1 Diphenylmethyl radicals / Steric effects Additions of the substituted diphenylmethyl radicals Arl-Ar'CR 2 (R = CMe3, SiMe3, GeMe3, SnMe3, OSiMe3, CF3, CO'Me, CN) to various acrylonitriles CHZ=C(X)CN 3 (X = SMe, SiPr, StBu, OAc, OSiMe,, OSiEt3, OMe, OEt) lead to 1
Enantiomerically pure trans-1,2-disubstituted cyclopentanes in a 98:1:1 ratio, while 11d was formed from 9d in a 99:1 ratio, both in 87 % yield. The configuration of the major products 14 and cyclohexanes 15 bearing three stereogenic centers can be synthesized highly selectively by Lewis acid induce