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ChemInform Abstract: Synthesis of Enantiomerically Pure trans-1,2-Disubstituted Cyclopentanes and Cyclohexanes by Intramolecular Allylsilane Addition to Chiral Alkylidene-1,3-dicarbonyl Compounds.

✍ Scribed by L. F. TIETZE; C. SCHUENKE


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
30
Category
Article
ISSN
0931-7597

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Synthesis of Enantiomerically Pure trans
✍ Lutz F. Tietze; Christian SchΓΌnke πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 277 KB πŸ‘ 2 views

Enantiomerically pure trans-1,2-disubstituted cyclopentanes in a 98:1:1 ratio, while 11d was formed from 9d in a 99:1 ratio, both in 87 % yield. The configuration of the major products 14 and cyclohexanes 15 bearing three stereogenic centers can be synthesized highly selectively by Lewis acid induce