Fragmentation of sesquiterpene lactones related to leucomisin
β Scribed by V. N. Plugar'; Ya. V. Rashker; I. M. Saitbaeva; A. Mallabaev
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 309 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0009-3130
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The chemical transformation of santonin into an elemane bis-lactone structurally related to the antitumour compound vemolepin is reported. The transformation of ring A of santonin into a hemiacetal ~-lactone was achieved in eleven steps. The spectroscopic characteristics of the synthetic product obt