Fragile X mental retardation protein interacts with TDG
β Scribed by Yuting Chen; B. Bardoni; Ming Yu; Ning Zhu; Guanyun Wu; J. L. Mandel; Yan Shen
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 348 KB
- Volume
- 45
- Category
- Article
- ISSN
- 1001-6538
No coin nor oath required. For personal study only.
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## Abstract Fragile X mental retardation is a disease caused by the loss of function of a single RNAβbinding protein, FMRP. Identifying the RNA targets recognized by FMRP is likely to reveal much about its functions in controlling some aspects of memory and behavior. Recent evidence suggests that o
We report an extended family in which two brothers with a fragile X chromosome are mentally retarded while a third brother with the fragile site is both phenotypically and mentally normal. The study of six probes detecting restriction fragment length polymorphisms on either sides of the fragile site