Fragile site Xq27.3 in a family without mental retardation
β Scribed by Dennis R. Romain; Cyril J. Chapman
- Book ID
- 115090373
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 239 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0009-9163
No coin nor oath required. For personal study only.
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We report an extended family in which two brothers with a fragile X chromosome are mentally retarded while a third brother with the fragile site is both phenotypically and mentally normal. The study of six probes detecting restriction fragment length polymorphisms on either sides of the fragile site
Data are presented suggesting that the form of X-linked mental retardation with macro-orchidism and the form associated with a fragile site at Xq27 or 28 are the same entity.