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Fractionation of a human serum albumin preparation and the salicylate binding characteristics

✍ Scribed by Naomi I., Nakano; Shigenori, Yamaguchi; Yoshimitsu, Shimamori; Yukio, Fujimoto

Book ID
122321858
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
774 KB
Volume
7
Category
Article
ISSN
0378-5173

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## Abstract When drug‐protein binding data are evaluated thermodynamically standard free energy (Ξ”GΒ°), standard enthalpy (Ξ”HΒ°) and standard entropy (Ξ”SΒ°) are usually estimated from association constants __(K__~a~) derived from binding data obtained at only two temperatures. Estimation of Ξ”HΒ° involv