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Binding of clometacin to human serum albumin: Interactions with clofibrate, indomethacin, salicylic acid and warfarin

✍ Scribed by R. Zini; J. Barre; P. D'Athis; J.P. Tillement


Book ID
115777031
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
558 KB
Volume
32
Category
Article
ISSN
0006-2952

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## Abstract When drug‐protein binding data are evaluated thermodynamically standard free energy (Ξ”GΒ°), standard enthalpy (Ξ”HΒ°) and standard entropy (Ξ”SΒ°) are usually estimated from association constants __(K__~a~) derived from binding data obtained at only two temperatures. Estimation of Ξ”HΒ° involv