## Abstract When drugβprotein binding data are evaluated thermodynamically standard free energy (ΞGΒ°), standard enthalpy (ΞHΒ°) and standard entropy (ΞSΒ°) are usually estimated from association constants __(K__~a~) derived from binding data obtained at only two temperatures. Estimation of ΞHΒ° involv
β¦ LIBER β¦
Effect of sodium oleate on salicylic acid binding to human serum albumin
β Scribed by Peter A. Schwartz; Douglas S. Greene; C. T. Rhodes
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 409 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0022-3549
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The reversible binding of ethacrynic acid was characterized by a difference circular dichroism method. A 2/1 stoichiometry was determined for the [drug]/[HSA] (human serum albumin) complex. The reversible binding of ethacrynic acid to HSA determines direct competition with ligands that selectivity b