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FOXP3+ regulatory T cells: Current controversies and future perspectives

✍ Scribed by Alison H. Banham; Fiona M. Powrie; Elisabeth Suri-Payer

Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 129 KB
Volume: 36
Category: Article
ISSN: 0014-2980
DOI: 10.1002/eji.200636459

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## Abstract The transcription factor FOXP3 is critical for development and function of regulatory T cells (Treg). Their number and functioning appears to be crucial in the prevention of autoimmunity and allergy, but also to be a negative prognostic marker for various solid tumors. Although expressi