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Four-mode gating model of fast inactivation of sodium channel Nav1.2a

โœ Scribed by Tobias Huth; Johann Schmidtmayer; Christian Alzheimer; Ulf-Peter Hansen

Book ID
106110169
Publisher
Springer
Year
2008
Tongue
English
Weight
815 KB
Volume
457
Category
Article
ISSN
0031-6768

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โœ Stephen I. Levin; Miriam H. Meisler ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 229 KB

## Abstract The sodium channel gene __Scn8a__ encodes the channel Na~V~1.6, which is widely distributed in the central and peripheral nervous system. Na~V~1.6 is the major channel at the nodes of Ranvier in myelinated axons. Mutant alleles of mouse __Scn8a__ result in neurological disorders includi