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Evidence of a physiological role for use-dependent inactivation of NaV1.8 sodium channels

โœ Scribed by Reese S. Scroggs

Book ID
110116090
Publisher
Cambridge University Press
Year
2008
Tongue
English
Weight
153 KB
Volume
586
Category
Article
ISSN
0022-3751

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## Abstract The sodium channel gene __Scn8a__ encodes the channel Na~V~1.6, which is widely distributed in the central and peripheral nervous system. Na~V~1.6 is the major channel at the nodes of Ranvier in myelinated axons. Mutant alleles of mouse __Scn8a__ result in neurological disorders includi