✦ LIBER ✦

Formation of ( S )-5-Cyclohexyl-5-phenyl-1,3-dioxolane-2,4-dione: A Key Intermediate in the Synthesis of ( S )-Oxybutynin Hydrochloride †

✍ Scribed by Vandenbossche, Charles P.; de Croos, Philomen; Singh, Surendra P.; Bakale, Roger P.; Wagler, Thomas R.

Book ID: 118002176
Publisher: American Chemical Society
Year: 2010
Tongue: English
Weight: 267 KB
Volume: 14
Category: Article
ISSN: 1083-6160
DOI: 10.1021/op100021w

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Microbial asymmetric reduction of (RS)-2

Microbial asymmetric reduction of (RS)-2-(4-methoxyphenyl)-1,5-benzothiazepin-3,4(2H,5H)-dione, the key intermediate in the synthesis of diltiazem hydrochloride

✍ Hiroaki Matsumae; Hiroshi Douno; Shinichi Yamada; Takuo Nishida; Yasuhiko Ozaki; 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 626 KB

A New Synthesis of (4R, 5S)-2,2-Dimethyl

A New Synthesis of (4R, 5S)-2,2-Dimethyl-5-[(Z)-2-pentenyl]-1,3-dioxolane-4-carboxaldehyde

✍ Sharma, P. K. ;Srivastava, S. K. ;Sharma, S. 📂 Article 📅 1995 🏛 Taylor and Francis Group 🌐 English ⚖ 237 KB

Production of (2S,3S)-2,3-dihydro-3-hydr

Production of (2S,3S)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one, a key intermediate for diltiazem synthesis, by Bakers' yeast-mediated reduction

✍ Tadashi Kometani; Yukiko Sakai; Hiroaki Matsumae; Takeji Shibatani; Ryuichi Mats 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 653 KB

Synthesis, anticancer activity and toxic

Synthesis, anticancer activity and toxicity of a water-soluble 4S,5S-derivative of heptaplatin, cis-{Pt(II)[(4S,5S)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane]·(3-hydroxyl-cyclobutane-1,1-dicarboxylate)}

✍ Liu, Weiping; Jiang, Jing; Xie, Chengying; Hou, Shuqian; Quan, Haitian; Ye, Qing 📂 Article 📅 2014 🏛 Elsevier Science 🌐 English ⚖ 610 KB

Synthesis of 14C-labeled 3-{[1-ethoxycar

Synthesis of 14C-labeled 3-{[1-ethoxycarbonyl-3-phenyl-(1S)-phenyl-(1S)-propyl]amino}-2,3,4,5-tetrahydro-2-oxo-1H-1-(3S)-benzazepine-1-acetic acid hydrochloride ([14C]CGS 14824A)

✍ Naba K. Chaudhuri; Russell Patera; Bohdan Markus; Ming-Sang Sung 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 French ⚖ 334 KB

The title compound, CGS 148248, was synthesized with a '%-label in the azepine ring in 14 steps starting with l-bromo-3-phenylpropane (1> and K1%N in an overall yield of 1.31%. The reaction of I with K 1 k N yielded the nitrile 2 which upon hydrolysis followed by ring closure gave a-tetral~ne-l-~~c

An Improved Process for the Synthesis of

An Improved Process for the Synthesis of 5-Bromo-3-(1-methylpiperidin-4-yl)-1 H -indole: A Key Intermediate in the Synthesis of Naratriptan Hydrochloride

✍ Shashikumar, Nellisara D.; Krishnamurthy, Ganga Naika; Rao K, Sundara Raj; Shrid 📂 Article 📅 2010 🏛 American Chemical Society 🌐 English ⚖ 184 KB