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Formation of leukotrienes and hydroxy acids by human neutrophils and platelets exposed to monosodium urate

✍ Scribed by Charles N. Serhan; Ulf Lundberg; Gerald Weissman; Bengt Samuelsson


Book ID
119049728
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
967 KB
Volume
27
Category
Article
ISSN
0090-6980

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We studied the capacities of naked and proteincoated monosodium urate (MSU) crystals to stimulate superoxide anion (Ozr) release by human polymorphonuclear leukocytes (PMN). Uncoated MSU stimulated significant Oz2 production by cytochalasin B-treated PMN. Precoating MSU with IgG caused an increase i