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Formation of leukotriene C4 by human leukocytes exposed to monosodium urate crystals

✍ Scribed by Charles N. Serhan; Ulf Lundberg; Jan Åke Lindgren; Gerald Weissmann; Bengt Samuelsson


Book ID
115915860
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
385 KB
Volume
167
Category
Article
ISSN
0014-5793

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We studied the capacities of naked and proteincoated monosodium urate (MSU) crystals to stimulate superoxide anion (Ozr) release by human polymorphonuclear leukocytes (PMN). Uncoated MSU stimulated significant Oz2 production by cytochalasin B-treated PMN. Precoating MSU with IgG caused an increase i