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Formation of hydrogen bonds precedes the rate-limiting formation of persistent structure in the folding of ACBP

✍ Scribed by Kaare Teilum; Birthe B Kragelund; Jens Knudsen; Flemming M Poulsen


Book ID
115630451
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
213 KB
Volume
301
Category
Article
ISSN
0022-2836

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✍ Michel E. Goldberg; Yvonne Guillou πŸ“‚ Article πŸ“… 2008 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 512 KB

## Abstract To assess the respective roles of local and long‐range interactions during protein folding, the influence of the native disulfide bonds on the early formation of secondary structure was investigated using continuous‐flow circular dichroism. Within the first 4 ms of folding, lysozyme wit