✦ LIBER ✦

Formation of additional contacts of chromosome with membrane in the process of DNA repair synthesis in bacterial cells

✍ Scribed by V. G. Bezlepkin; Yu. Yu. Malinovsky; A. I. Gaziev

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 869 KB
Volume: 23
Category: Article
ISSN: 0233-111X
DOI: 10.1002/jobm.19830231002

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✦ Synopsis

An increase in the amount of membrane-bouqd DNA was found in B. subtitilia cells with UVinduced DNA repair synthesis as compared to untreated cells. It was shown that DNA repair synthesis occurred in DNA membrane complexes (DMC) formed during W-irradiation. UV-induced formation of DMC was observed in aells of wild type strainbwhich were capable of repairing damaged DNA but not in a mutant defective in DNA-polymerase I. It was demonstrated that DNApolymerase I is located on the membrane of B. subtiiis cells. This suggested a participation of DNA.

lymerase I in binding of the chromosome to the membrane in W-irradiated cells. UV-induced 332 -337.

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