An investigation of the reaction of tryptophan and its methyl ester with ninhydrin has been conducted. In the reaction of tryptophan with ninhydrin only one product, yohimbanone (1), is isolated. In contrast, an intermediate, Pictet -Spengler product 3, is isolated from the reaction of tryptophan me
Formation of a fluorophosphine complex by a novel rearrangement
β Scribed by R.C Dobbie
- Publisher
- Elsevier Science
- Year
- 1973
- Weight
- 83 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0020-1650
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## Summany The cyclohe.xenop\_vridinio cephafosporin 1 ICefqinomeI reacts in the presence of a base irreversibly to the spiro compound 3. The structure has been elucidated by twodimensional NMR-experiments. The energy of the possible stereoisomers of \_3 has been calculated by MhDO.
would be expected to preponderate very largely[Ig1, which accords with the experiment (see above). According to Scheme 2 the same situation should occur on Ag'-catalysis since there (13) [(I.?a)] is again postulated as intermediate: the almost identical o/p-ratio (see Table 1) is visible confirmatio