Formation and fragmentation of the [M + Na]+ ion of glycosides in fast atom bombardment mass spectrometry

✍ Scribed by Mitsuo Takayama; Toshio Fukai; Taro Nomura; Tatsuo Yamauchi

• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: English
• Weight: 479 KB
• Volume: 26
• Category: Article
• ISSN: 1076-5174
• DOI: 10.1002/oms.1210260709

✦ Synopsis

Positive-ion fast atom bombardment (FAB) mass spectra of &vowl a d steroid glycodes with sodium chloride added showed well known characteristic features of the appearaoce of [M + Nal' peaks, disapperrance of ( M + HI+ perks and a significant decrease in the peak beights of fragment iom Compared with tbe fcrtures in the FAB mass spectra of crown ethers with addition of salt, and above features suggest a compkxatioll between Na+ and the glycosides in matrix solutioa The B/E-constrnt linked scanning technique was rsed to obtain structural information of the ( M + Nal+ ion of the glycosides The B/E spectra gave tbe daughter-ion peaks, wggesting that coordination of Na+ with the b i d e s and triosides occurs at the sugar moiety, whereas the coordination with the moooglycosides occurs at the aglycow moiety, except for monoglycosides in which the aglycone moiety does not contain significant oxygen functional groups such as OH a d CO.