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Formatin of heterodimers of human-immunodeficiency-virus-type-1 reverse transcriptase by recombination of separately purified subunits

✍ Scribed by David K. STAMMERS; Carl K. ROSS; Haitham IDRISS; Denise M. LOWE

Book ID
115129331
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
444 KB
Volume
206
Category
Article
ISSN
1432-1327

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Inhibitory antibodies to the reverse transcriptase (RT) of human immunodeficiency virus type-1 (HIV-1) can be used to block the life cycle of the virus. We have isolated five different human single chain Fv (ScFv) antibodies specific for HIV-1 RT from an antibody phage display library. Three of thes