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Formal Asymmetric Synthesis of Echinopine A and B

✍ Scribed by Dr. Philippe A. Peixoto; Dr. Rene Severin; Dr. Chih-Chung Tseng; Prof. Dr. David Y.-K. Chen

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
334 KB
Volume
123
Category
Article
ISSN
0044-8249

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Formal Asymmetric Synthesis of Echinopin
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✍ Dr. Philippe A. Peixoto; Dr. Rene Severin; Dr. Chih-Chung Tseng; Prof. Dr. David 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 323 KB 👁 1 views
Asymmetric synthesis of (+)-pilosinine:
Asymmetric synthesis of (+)-pilosinine: a formal synthesis of (+)-pilocarpine
✍ Gideon Shapiro; Cai Chengzhi 📂 Article 📅 1992 🏛 Elsevier Science 🌐 French ⚖ 274 KB

An efficient asymmetric synthesis of enantiomerically pure (+)\_pilosinine 4 has been achieved in 6 steps from a known chiral bromoacyloxaxolidinone. The imidaxole alkaloid (+)-pilocarpine 1 and analogs have been the subject of considerable study of late due to their therapeutic potential as muscari